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Usoro ihe omimi nke Zolmitriptan: C16H21N3O2

Chemical IUPAC Aha: (S)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-otu

Nọmba CAS: 139264-17-8

Usoro nhazi:

Zolmitriptan

Zolmitriptan bụ agonist nke na-anabata serotonin nke 1B na 1D subtypes.Ọ bụ triptan, nke a na-eji agwọ ọrịa migraine na-enwe ma ọ bụ na-enweghị aura na isi ọwụwa ụyọkọ.Zolmitriptan bụ ihe nrụpụta tryptamine sịntetịt na-apụta dị ka ntụ ntụ ọcha nke na-agbaze n'ime mmiri.

Zomig bụ onye na-anabata ihe nnabata serotonin (5-HT) nke a na-eji na ọgwụgwọ migraines na ndị okenye.Ihe na-arụ ọrụ na Zomig bụ zolmitriptan, onye na-anabata ihe na-anabata serotonin.A na-ekewa ya dị ka triptan, nke a kwenyere na ọ na-ebelata ihe mgbu nke migraine site na ibelata ọzịza na ibelata arịa ọbara.Dị ka onye na-anabata serotonin agonist, Zomig na-akwụsịkwa mgbaàmà mgbu na-ezigara ụbụrụ ụbụrụ ma gbochie mwepụta nke ụfọdụ kemịkalụ n'ime ahụ nke na-akpata mgbaàmà nke migraine, gụnyere isi mgbu, ọgbụgbọ, na mmetụta nke ìhè na ụda.A na-egosi Zomig maka migraines na ma ọ bụ na-enweghị aura, ihe ngosi anya ma ọ bụ ihe mgbaàmà ụfọdụ ndị nwere migraine na-enweta tupu isi mgbu.

Ojiji nke Zolmitriptan

A na-eji Zolmitriptan mee ihe maka ọgwụgwọ dị ukwuu nke migraines na ma ọ bụ na-enweghị aura na ndị okenye.Ezubere Zolmitriptan maka ọgwụgwọ prophylactic nke migraine ma ọ bụ maka iji ya na njikwa nke hemiplegic ma ọ bụ basil migraine.

Zolmitriptan dị ka mbadamba nkume a na-eloda, mbadamba ụrọ na-agbasa, na ịgba imi, na doses nke 2.5 na 5 mg.Ndị mmadụ na-enweta migraines site na aspartame ekwesịghị iji mbadamba nkume na-agbasasị (Zomig ZMT), nke nwere aspartame.

Dị ka ọmụmụ nke ndị ọrụ afọ ofufo ahụike siri kwuo, iri nri yiri ka ọ nweghị mmetụta dị ukwuu na irè Zolmitriptan na ma ndị nwoke ma ndị nwanyị.

Zolmitriptan dị na Zomig na-ejikọ ụfọdụ ndị na-anabata serotonin.Ndị na-eme nchọpụta kwenyere na Zomig na-arụ ọrụ site na ijikọta ndị a na-anabata ya na neurons (sel nerve) na arịa ọbara na ụbụrụ, na-eme ka arịa ọbara na-egbochi ma na-egbochi kemịkalụ nke ga-eme ka mbufụt.Zomig na-ebelatakwa ihe ndị na-akpalite mgbu isi na nke nwere ike itinye aka na mgbaàmà ndị ọzọ nke migraine, dị ka ọgbụgbọ, mmetụta nke ìhè, na mmetụta nke ụda.Zomig na-arụ ọrụ kacha mma mgbe a na-ewere ya na akara mbụ nke migraine.Ọ naghị egbochi migraine ma ọ bụ belata ọnụ ọgụgụ migraine ọgụ ị nwere.

Mmetụta nke Zolmitriptan

Dị ka ọgwụ niile, Zomig nwere ike ịkpata mmetụta ndị na-atụghị anya ya.Mmetụta kachasị emetụta ndị mmadụ na-ewere mbadamba nkume Zomig bụ ihe mgbu, njigide ma ọ bụ nrụgide n'olu, akpịrị, ma ọ bụ agba;dizziness, tingling, adịghị ike ma ọ bụ enweghị ume, ihi ụra, mmetụta nke okpomọkụ ma ọ bụ oyi, ọgbụgbọ, mmetụta dị arọ, na ọnụ nkụ.Mmetụta ndị na-emekarị nke ndị mmadụ na-agba mmiri Zomig bụ ihe na-adịghị ahụkebe, tingling, dizziness, na mmetụta nke akpụkpọ ahụ, karịsịa akpụkpọ ahụ dị n'akụkụ imi.

Ntụaka

https://en.wikipedia.org/wiki/Zolmitriptan

https://www.ncbi.nlm.nih.gov/pubmed/16412157

https://www.ncbi.nlm.nih.gov/pubmed/18788838

https://www.ncbi.nlm.nih.gov/m/pubmed/10473025

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